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subject: As states ease restrictions, doctors warn of 'worse than second wave' if COVID norms not followed: All you need to know-India News , Firstpost
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subject: Colombia's COVID-19 death toll tops 100,000
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subject: Michigan confirms 25 cases of COVID-19's highly contagious delta variant
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subject: Euro 2020: Scotland's Billy Gilmour to miss crucial Croatia game because of COVID-19
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subject: Hungary's Sinopharm Controversy Gaining Heat Over Low Antibody Tests
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subject: India's vaccination pace expected to dwindle from first day record
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subject: S. Korea Reports 261 New Variant COVID-19 Cases
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subject: Covid boosters in the fall? As calls grow for third shots, here's what you need to know
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subject: Man charged after 3-year-old dies from eating poisoned breakfast cereal
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subject: Fires destroy 2 churches on Canadian Indigenous reserves
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subject: North Carolina ballot probe figure pleads to benefit fraud
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subject: Israel urges vaccination for all teens, citing delta variant
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subject: CP threatened lawsuit against safety watchdog after investigator spoke out about deadly crash
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subject: Canada eases its hotel-quarantine rule for vaccinated citizens flying in from abroad.
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subject: Clearfield Man in Custody After Stealing Ambulance and Leading Police on Chase
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subject: German competition watchdog launches Apple investigation
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subject: Some international travel restrictions easing for fully vaccinated people with proof
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subject: With its aggressive financial strategy, Disneyland is pricing out its most loyal fans
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subject: Iowa abortion law requiring 24-hour waiting period permanently blocked by district court
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subject: 'Living fossil' fish surprises scientists with 100-year lifespan | CBC News
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subject: Death of Romany man knelt on by Czech police compared to that of George Floyd
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subject: 70 percent of Californians over 12 have received one shot of coronavirus vaccine
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subject: 'Vaccine or jail?': Duterte warns as COVID's Delta variant surges | Coronavirus pandemic News
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subject: Geriatric penguin at St. Louis Zoo gets custom shoes to help with arthritis
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subject: Two-thirds of Canadians say governments shouldn't lift all COVID-19 restrictions
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subject: The White House Publicly Acknowledges the U.S. is Likely to Miss Biden's July 4 Vaccination Goal.
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subject: CDC: Nearly every adult COVID-19 death is now "entirely preventable" thanks to vaccines
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subject: Turkey lowers vaccine eligibility age to 25
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subject: Lumber Prices Are Finally Dropping After They Soared During The Pandemic
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subject: Morgan Stanley will bar workers without Covid vaccinations from most New York offices beginning July 12
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subject: First wave COVID-19 data underestimated pandemic infections
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subject: Man goes fishing during 5-hour closure of La. bridge following 18-wheeler crash
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subject: More than 150 Houston Methodist employees resign or are fired over COVID vaccine mandate
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subject: Arkansas has biggest 1-day jump in virus cases since March
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subject: Houston Hospital Workers Lose Their Jobs After Not Getting The COVID Vaccine
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subject: 153 Houston Methodist Workers Out of Job After Vaccine Protest
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subject: LinkedIn blocks profiles from view in China if sensitive topics mentioned
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subject: Winnipeg adults cancelling Pfizer vaccine bookings to make room for youth amid supply issues
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subject: Some used vehicles now cost more than original sticker price
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subject: Louisiana's Democratic governor vetoes anti-trans sports ban, calling it discriminatory
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subject: Texas governor vetoes bill protecting dogs from abuse [News]
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subject: Saudi operatives who killed Jamal Khashoggi received paramilitary training in U.S.
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subject: Hammond police officer sentenced to 15 years in prison for having sex with a child, prosecutors say
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subject: With eight million shots in a day, India tries to energize its vaccination effort.
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subject: Two additional manufacturing sites for BioNTech/Pfizer's COVID-19 vaccine - European Medicines Agency
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subject: COVID-19 may promote the spread of drug-resistant 'superfungus'
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subject: COVID-19's global death toll this year has already surpassed 2020's count
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subject: Vaccines stay effective in reducing symptoms in Delta-hit Indonesia: Sinovac
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subject: Anti-vax group mounts legal blitz to sow disinformation against vaccinations
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subject: New Zealand pauses quarantine-free travel from NSW as state records ten new local COVID-19 cases
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subject: China issues furious response after Canada condemns human rights record
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subject: India reports new 'Delta plus' coronavirus variant of concern
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subject: Poland introduces mandatory seven-day quarantine for UK arrivals
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subject: Delta coronavirus variant: scientists brace for impact
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subject: The push to make 'ecocide' an international crime takes a big step forward
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Geneva/Johannesburg/Paris: The World Health Organization (WHO) and its COVAX partners are working with a South African consortium comprising Biovac, Afrigen Biologics and Vaccines, a network of universities and the Africa Centres for Disease Control and Prevention (CDC) to establish its first COVID mRNA vaccine technology transfer hub.

The move follows WHO's global  call for Expression of Interest (EOI) on 16 April 2021 to establish COVID mRNA vaccine technology transfer hubs to scale up production and access to COVID vaccines. Over the coming weeks, the partners will negotiate details with the Government of South Africa and public and private partners inside the country and from around the world.

South African President Cyril Ramaphosa said: "The COVID-19 pandemic has revealed the full extent of the vaccine gap between developed and developing economies, and how that gap can severely undermine global health security. This landmark initiative is a major advance in the international effort to build vaccine development and manufacturing capacity that will put Africa on a path to self determination. South Africa welcomes the opportunity to host a vaccine technology transfer hub and to build on the capacity and expertise that already exists on the continent to contribute to this effort."

"This is great news, particularly for Africa, which has the least access to vaccines," said Dr Tedros Adhanom Ghebreyesus, WHO Director-General. "COVID-19 has highlighted the importance of local production to address health emergencies, strengthen regional health security and expand sustainable access to health products."

The announcement follows the recent visit to South Africa by the President of France, Mr Emmanuel Macron, who said his country was committed to supporting efforts in Africa to scale up local manufacturing capacity of COVID-19 vaccines and other medical solutions.

"Today is a great day for Africa. It is also a great day for all those who work towards a more equitable access to health products. I am proud for Biovac and our South African partners to have been selected by WHO, as France has been supporting them for years," said President Macron. "This initiative is the first of a long list to come, that we will keep supporting, with our partners, united in the belief that acting for global public goods is the fight of the century and that it cannot wait."

Technology transfer hubs are training facilities where the technology is established at industrial scale and clinical development performed. Interested manufacturers from low- and middle-income countries can receive training and any necessary licenses to the technology. WHO and partners will bring in the production know-how, quality control and necessary licenses to a single entity to facilitate a broad and rapid technology transfer to multiple recipients.

The technology transfer hub will benefit from the Medicines Patent Pool's (MPP's) vast experience of intellectual property (IP) management and issuing of IP licenses. MPP is also assisting WHO to negotiate with technical partners and supporting in the governance of the hubs.

Biovac is a bio-pharmaceutical company that is the result of a partnership formed with the South African government in 2003 to establish local vaccine manufacturing capability for the provision of vaccines for national health management and security.

Afrigen Biologics and Vaccines is a biotechnology company focuses on product development, bulk adjuvant manufacturing and supply and distribution of key biologicals to address unmet healthcare needs.

The organizations complement one another, and can each take on different roles within the proposed collaboration: Biovac will act as developer, Afrigen as manufacturer and a consortium of universities as  academic supporters providing mRNA know-how, and Africa CDC for technical and regional support.

The South African consortium benefits from having existing operating facilities that have spare capacity and because it has experience in technology transfers. It is also a global hub that can start training technology recipients immediately.

Other hubs in the pipeline

WHO's April call for expressions of interest has so far generated 28 offers to either provide technology for mRNA vaccines or to host a technology hub or both. There have been 25 expressions of interest from low- and middle-income country respondents who could receive the technology to produce mRNA vaccines.

Over the coming weeks, WHO will continue the rolling evaluation of other proposals and identify additional hubs, as needed, to contribute to health security and equity in all regions.

Through the COVAX partnership, WHO will continue its assessment of potential mRNA technology donors and will launch subsequent calls for other technologies, such as viral vectors and proteins, in coming months.

WHO is also hosting the Local production forum this week, to identify strategies to expand pharmaceutical manufacturing capacity in low- and middle-income countries for COVID-19 and other priority diseases.



Geneva/Johannesburg/Paris: The World Health Organization (WHO) and its COVAX partners are working with a South African consortium comprising Biovac, Afrigen Biologics and Vaccines, a network of universities and the Africa Centres for Disease Control and Prevention (CDC) to establish its first COVID mRNA vaccine technology transfer hub.

The move follows WHO's global  call for Expression of Interest (EOI) on 16 April 2021 to establish COVID mRNA vaccine technology transfer hubs to scale up production and access to COVID vaccines. Over the coming weeks, the partners will negotiate details with the Government of South Africa and public and private partners inside the country and from around the world.

South African President Cyril Ramaphosa said: "The COVID-19 pandemic has revealed the full extent of the vaccine gap between developed and developing economies, and how that gap can severely undermine global health security. This landmark initiative is a major advance in the international effort to build vaccine development and manufacturing capacity that will put Africa on a path to self determination. South Africa welcomes the opportunity to host a vaccine technology transfer hub and to build on the capacity and expertise that already exists on the continent to contribute to this effort."

"This is great news, particularly for Africa, which has the least access to vaccines," said Dr Tedros Adhanom Ghebreyesus, WHO Director-General. "COVID-19 has highlighted the importance of local production to address health emergencies, strengthen regional health security and expand sustainable access to health products."

The announcement follows the recent visit to South Africa by the President of France, Mr Emmanuel Macron, who said his country was committed to supporting efforts in Africa to scale up local manufacturing capacity of COVID-19 vaccines and other medical solutions.

"Today is a great day for Africa. It is also a great day for all those who work towards a more equitable access to health products. I am proud for Biovac and our South African partners to have been selected by WHO, as France has been supporting them for years," said President Macron. "This initiative is the first of a long list to come, that we will keep supporting, with our partners, united in the belief that acting for global public goods is the fight of the century and that it cannot wait."

Technology transfer hubs are training facilities where the technology is established at industrial scale and clinical development performed. Interested manufacturers from low- and middle-income countries can receive training and any necessary licenses to the technology. WHO and partners will bring in the production know-how, quality control and necessary licenses to a single entity to facilitate a broad and rapid technology transfer to multiple recipients.

The technology transfer hub will benefit from the Medicines Patent Pool's (MPP's) vast experience of intellectual property (IP) management and issuing of IP licenses. MPP is also assisting WHO to negotiate with technical partners and supporting in the governance of the hubs.

Biovac is a bio-pharmaceutical company that is the result of a partnership formed with the South African government in 2003 to establish local vaccine manufacturing capability for the provision of vaccines for national health management and security.

Afrigen Biologics and Vaccines is a biotechnology company focuses on product development, bulk adjuvant manufacturing and supply and distribution of key biologicals to address unmet healthcare needs.

The organizations complement one another, and can each take on different roles within the proposed collaboration: Biovac will act as developer, Afrigen as manufacturer and a consortium of universities as  academic supporters providing mRNA know-how, and Africa CDC for technical and regional support.

The South African consortium benefits from having existing operating facilities that have spare capacity and because it has experience in technology transfers. It is also a global hub that can start training technology recipients immediately.

Other hubs in the pipeline

WHO's April call for expressions of interest has so far generated 28 offers to either provide technology for mRNA vaccines or to host a technology hub or both. There have been 25 expressions of interest from low- and middle-income country respondents who could receive the technology to produce mRNA vaccines.

Over the coming weeks, WHO will continue the rolling evaluation of other proposals and identify additional hubs, as needed, to contribute to health security and equity in all regions.

Through the COVAX partnership, WHO will continue its assessment of potential mRNA technology donors and will launch subsequent calls for other technologies, such as viral vectors and proteins, in coming months.

WHO is also hosting the Local production forum this week, to identify strategies to expand pharmaceutical manufacturing capacity in low- and middle-income countries for COVID-19 and other priority diseases.

subject: WHO supporting South African consortium to establish first COVID mRNA vaccine technology transfer hub
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subject: Coronavirus in Israel: Three vaccinated IDF personnel infected with COVID
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subject: Landmark trial in France over avalanche of threats against teen critic of Islam
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subject: Delta plus variant of coronavirus spreading in India, 3 states report cases: Report | Latest News India
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subject: New Coronavirus Variants Are Urgently Being Tracked around the World
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subject: U.S. to investigate Indigenous boarding school burial sites after Canada's discovery
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subject: Japan reaches Suga's target of 1 million vaccine doses per day
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subject: NSW Covid update: greater Sydney hit with new restrictions as state announces 16 coronavirus cases
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subject: COVID-19 measures still needed as vaccines not 'absolutely perfect,' Tam warns
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subject: Warren Buffett gives away another $4.1 billion, resigns as trustee at Gates Foundation
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subject: California's historic drought is causing drinking water to taste like dirt. Just 'add lemon,' officials say
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subject: Almost 900 Secret Service employees were infected with COVID
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subject: Canadian study finds mRNA vaccines produce more COVID-19 antibodies than AstraZeneca
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subject: Covid: 23,000 lives could have been saved in first wave if England had been put on lockdown a week earlier
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subject: Tanzania to offer alternative education for school dropouts including pregnant girls -official
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subject: [Belgium] Coronavirus: 70% of 18+ have received a first dose of the vaccine (in French)
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subject: Ugandan Olympic team quarantined in Japan after virus case
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subject: 6 LA Sheriff's Deputies accused of brutally beating black man, dislodging eyeball out of its socket.
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subject: Home sales fall for fourth straight month as affordability squeezes buyers out - The median price of an existing home in May was $350,300, up 23.6 percent since May 2020.
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subject: Oklahoma woman dies in apparent pit bull attack, deputies say
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subject: Video: Fauci warns kids 'more likely' to be infected by Delta variant
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subject: CDC finds more cases of rare heart inflammation than expected after Covid vaccine shots
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subject: Call to speed up Covid jabs as Delta variant spreads across Europe
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subject: Michigan drops COVID-19 safety restrictions in most workplaces
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subject: A Black WWII veteran who was denied the Purple Heart due to racism finally receives the honor at 99
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subject: Supreme Court Restricts Police Powers To Enter A Home Without A Warrant
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subject: Police Chief: Slain Colorado officer was ambushed
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subject: Jailed hero of 'Hotel Rwanda' claims he was tortured at 'slaughterhouse' after arriving in Kigali
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subject: California's COVID-19 vaccinations rise as U.S. struggles. Does the lottery deserve credit?
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subject: Why India is concerned about 'Delta plus' variant and a third wave - as 41 cases detected in UK
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subject: Highly contagious Delta variant​ could cause next COVID-19 wave: "This virus will still find you"
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subject: Black Campus Police Officers Say They Suffered 'Unbearable' Racism
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An early summer widespread heatwave across the drought-stricken western United States smashed records in seven states as temperatures cleared 100 degrees Fahrenheit for days on end. 

    An early summer widespread heatwave across the drought-stricken western United States smashed records in seven states as temperatures cleared 100 degrees Fahrenheit for days on end. 
    subject: Record-breaking June 2021 heatwave impacts the U.S. West

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