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Event
subject: Moth species not seen since 1912 found in luggage at Detroit airport
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subject: Kidnapped woman saved after leaving note at KFC asking for help
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subject: The U.S. may be in a silent covid surge
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subject: FDA to act quickly on Moderna's COVID vaccine bid for youngest kids -Califf
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subject: U.S. CDC advisers recommend COVID booster for children 5-11
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subject: U.S. CDC says COVID vaccine-related myocarditis much lower for children than teens
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subject: Mystery issue experienced on NASA's Voyager 1 probe from 1977
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subject: Illinois man convicted of giving son rifle he used to kill 4
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subject: Spain to allow girls over 16 to opt for abortions without parental consent
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subject: Dallas Koreatown hair salon shooting suspect had 'delusional fear of Asians,' police records say
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subject: Vangelis, composer of Chariots of Fire and Blade Runner soundtracks, dies aged 79
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subject: Afghanistan's female TV presenters must cover their faces, say Taliban - BBC News
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subject: 12-year-old handcuffed by Montreal police says he 'felt terrified,' father plans to sue
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subject: Price fixing has sent Realtor commissions soaring in an already hot market, lawsuit alleges
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subject: Ukraine liberates 23 settlements in two weeks – General Staff
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subject: Turkey has told allies it's a 'no' to Sweden and Finland's NATO bid - Erdogan | Reuters
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subject: Senate Blocks Restaurant Industry Push for New Covid Relief
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subject: Haven't had COVID yet? It could be more than just luck
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subject: What's sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both?
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subject: North Korea's suspected COVID-19 caseload nears 2 million
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subject: Why isn't there a nasal vaccine for Covid-19 yet?
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subject: High purchase price and misinformation barrier to EV purchase
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subject: L.A. coronavirus hospitalizations rise, outbreaks increase
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subject: Florida man gets life in prison for traveling to Vietnam to sexually abuse minors
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subject: Unarmed 13-Year-Old Shot By Chicago Cops During Foot Chase On West Side
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subject: The U.S. surpasses 1 million Covid deaths, the world's highest known total.
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subject: CDC recommends Pfizer booster shot for kids ages 5 to 11 as Covid cases rise across the U.S.
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subject: Melvin Capital to shut after heavy losses on meme stocks, market slump
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subject: Man Arrested In Dave Chappelle Attack Charged With Attempted Murder In Alleged Stabbing Of Roommate
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subject: Report: Elon Musk exposed himself to SpaceX flight attendant, according to documents
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subject: Just before Buffalo shooting, 15 users signed into suspect's chatroom, says person familiar with review
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subject: Almost as contagious as measles: Coronavirus spins out worrisome new mutations
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subject: Rents in the US just hit another record high
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subject: NY COVID Hospitalizations at 3-Month High, Rise 25% in 10 Days as Fifth Wave Intensifies
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subject: Medical experts offer warning amid rise in cases of flu and COVID-19
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subject: Oklahoma passes bill banning most abortions after conception
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subject: New York Supreme Court ruling reinstates law banning police officers from using chokeholds during arrests
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subject: Your Dog Is Not Ready for You to Return to the Office
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subject: Oklahoma passes bill banning most abortions after conception.
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subject: Blackouts possible this summer due to heat and extreme weather, officials warn
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subject: China's international schools hit by exodus of teachers dejected by COVID curbs
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subject: Ex-deputy gets 18 years after detainees drown in locked van
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subject: Disaster declared in Texas county as wildfire balloons to 7,000 acres
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subject: Google 'private browsing' mode not really private, Texas lawsuit says
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subject: 1 dead, 1 in critical condition in shooting after Tennessee high school graduation
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subject: Boston reports 'significant increase' in COVID cases, hospitalizations; Massachusetts reports nearly 5,000 new cases
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subject: Estranged husband shot wife, 4-year-old daughter, mother-in-law before killing himself, sheriff says
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subject: First batch of infant formula headed to US from Switzerland
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subject: Judge approved up to $31M in bonuses for Purdue employees
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subject: U.S. CDC backs COVID boosters for children 5 to 11
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subject: 1,000 cases of new Omicron subvariant BA.2.20 found in Ontario: PHO
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subject: Why Adams Is Rejecting Mask Mandates as Covid Cases Rise in New York
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subject: Highland Park to return seized building after asking for new police cars in exchange
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subject: 'We are going to die': Food shortages worsen Sri Lanka crisis
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subject: Toddler dies after being found in vehicle at Tenn. daycare
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subject: How long does COVID-19 linger in your body? New report offers clues.
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subject: A clue about why Covid is more deadly for men: Estrogen may play protective role
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body:

Today, the World Health Organization (WHO) issued an emergency use listing (EUL) for CONVIDECIA, a vaccine manufactured by CanSino Biologics, China, adding to a growing portfolio of vaccines validated by WHO for the prevention of COVID-19 caused by SARS-CoV-2.

WHO's EUL procedure assesses the quality, safety and efficacy of COVID-19 vaccines as a prerequisite for COVAX vaccine supply. It also allows countries to expedite their own regulatory approval to import and administer COVID-19 vaccines.

CONVIDECIA was assessed under the WHO EUL procedure based on the review of data on quality, safety, efficacy, a risk management plan, programmatic suitability and a manufacturing site inspection conducted by WHO. The Technical Advisory Group for Emergency Use Listing, convened by WHO and made up of regulatory experts from around the world, has determined that the vaccine meets WHO standards for protection against COVID-19 and that the benefits of the vaccine far outweigh risks.

CONVIDECIA is based on a modified human adenovirus that expresses the spike S protein of SARS-CoV-2. It is administered as a single dose.

CONVIDECIA was also reviewed earlier this month by WHO's Strategic Advisory Group of Experts on Immunization (SAGE), which formulates vaccine specific policies and recommendations for vaccines' use in populations (i.e. recommended age groups, intervals between shots, specific groups such as pregnant and lactating women).

The SAGE recommends use of the vaccine as a single (0.5ml) dose, in all age groups 18 and above. 

CONVIDECIA was found to have 64% efficacy against symptomatic disease and 92% against severe COVID-19.

WHO emergency use listing

The emergency use listing (EUL) procedure assesses the suitability of novel health products during public health emergencies. The objective is to make medicines, vaccines and diagnostics available as rapidly as possible to address the emergency while adhering to stringent criteria of safety, efficacy and quality. The assessment weighs the threat posed by the emergency as well as the benefit that would accrue from the use of the product against any potential risks.

The EUL pathway involves a rigorous assessment of late phase II and phase III clinical trial data as well as substantial additional data on safety, efficacy, quality and a risk management plan. These data are reviewed by independent experts and WHO teams who consider the current body of evidence on the vaccine under consideration, the plans for monitoring its use, and plans for further studies.

As part of the EUL process, the company producing the vaccine must commit to continue to generate data to enable full licensure and WHO prequalification of the vaccine. The WHO prequalification process will assess additional clinical data generated from vaccine trials and deployment on a rolling basis to ensure the vaccine consistently meets the necessary standards of quality, safety and efficacy for broader availability.

See all EUL listings

SAGE

SAGE is the principal advisory group to WHO for vaccines and immunization. It is charged with advising WHO on overall global policies and strategies, ranging from vaccines and immunization technology, research and development, to delivery of immunization and its linkages with other health interventions. SAGE is concerned not just with childhood vaccines and immunization, but all vaccine-preventable diseases.

SAGE assesses evidence on safety, efficacy, effectiveness, impact and programmatic suitability, considering both individual and public health impact.  SAGE Interim recommendations for EUL products provide guidance for national vaccination policy makers.  These recommendations are updated as additional evidence becomes available and as there are changes to the epidemiology of disease and the availability of additional vaccines and other disease control interventions.

See SAGE interim recommendations

 



Today, the World Health Organization (WHO) issued an emergency use listing (EUL) for CONVIDECIA, a vaccine manufactured by CanSino Biologics, China, adding to a growing portfolio of vaccines validated by WHO for the prevention of COVID-19 caused by SARS-CoV-2.

WHO's EUL procedure assesses the quality, safety and efficacy of COVID-19 vaccines as a prerequisite for COVAX vaccine supply. It also allows countries to expedite their own regulatory approval to import and administer COVID-19 vaccines.

CONVIDECIA was assessed under the WHO EUL procedure based on the review of data on quality, safety, efficacy, a risk management plan, programmatic suitability and a manufacturing site inspection conducted by WHO. The Technical Advisory Group for Emergency Use Listing, convened by WHO and made up of regulatory experts from around the world, has determined that the vaccine meets WHO standards for protection against COVID-19 and that the benefits of the vaccine far outweigh risks.

CONVIDECIA is based on a modified human adenovirus that expresses the spike S protein of SARS-CoV-2. It is administered as a single dose.

CONVIDECIA was also reviewed earlier this month by WHO's Strategic Advisory Group of Experts on Immunization (SAGE), which formulates vaccine specific policies and recommendations for vaccines' use in populations (i.e. recommended age groups, intervals between shots, specific groups such as pregnant and lactating women).

The SAGE recommends use of the vaccine as a single (0.5ml) dose, in all age groups 18 and above. 

CONVIDECIA was found to have 64% efficacy against symptomatic disease and 92% against severe COVID-19.

WHO emergency use listing

The emergency use listing (EUL) procedure assesses the suitability of novel health products during public health emergencies. The objective is to make medicines, vaccines and diagnostics available as rapidly as possible to address the emergency while adhering to stringent criteria of safety, efficacy and quality. The assessment weighs the threat posed by the emergency as well as the benefit that would accrue from the use of the product against any potential risks.

The EUL pathway involves a rigorous assessment of late phase II and phase III clinical trial data as well as substantial additional data on safety, efficacy, quality and a risk management plan. These data are reviewed by independent experts and WHO teams who consider the current body of evidence on the vaccine under consideration, the plans for monitoring its use, and plans for further studies.

As part of the EUL process, the company producing the vaccine must commit to continue to generate data to enable full licensure and WHO prequalification of the vaccine. The WHO prequalification process will assess additional clinical data generated from vaccine trials and deployment on a rolling basis to ensure the vaccine consistently meets the necessary standards of quality, safety and efficacy for broader availability.

See all EUL listings

SAGE

SAGE is the principal advisory group to WHO for vaccines and immunization. It is charged with advising WHO on overall global policies and strategies, ranging from vaccines and immunization technology, research and development, to delivery of immunization and its linkages with other health interventions. SAGE is concerned not just with childhood vaccines and immunization, but all vaccine-preventable diseases.

SAGE assesses evidence on safety, efficacy, effectiveness, impact and programmatic suitability, considering both individual and public health impact.  SAGE Interim recommendations for EUL products provide guidance for national vaccination policy makers.  These recommendations are updated as additional evidence becomes available and as there are changes to the epidemiology of disease and the availability of additional vaccines and other disease control interventions.

See SAGE interim recommendations

 

subject: WHO validates 11th vaccine for COVID-19
Event
body:

The WHO interim recommendations for the use of the Cansino Ad5-nCoV-S vaccine against COVID-19 are now published.

 

Interim recommendations for use of the Cansino Ad5-nCoV-S vaccine against COVID-19

 



The WHO interim recommendations for the use of the Cansino Ad5-nCoV-S vaccine against COVID-19 are now published.

 

Interim recommendations for use of the Cansino Ad5-nCoV-S vaccine against COVID-19

 

subject: Cansino Ad5-nCoV-S vaccine recommendations for use
Event
body:

Nearly 18 months after the first administration of a COVID-19 vaccine, incredible progress has been made. Yet despite this progress, inequities between lower and higher income countries are continuing to cost lives and are prolonging the pandemic.

    Nearly 18 months after the first administration of a COVID-19 vaccine, incredible progress has been made. Yet despite this progress, inequities between lower and higher income countries are continuing to cost lives and are prolonging the pandemic.
    subject: COVAX calls for urgent action to close vaccine equity gap
    Event
    subject: Inside a growing movement of COVID deniers and conspiracists — including one Ontario cop — who are clogging the courts with 'legal gibberish'
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    subject: CDC Puts 87% of NY Counties, Including Whole City, at High COVID Risk; Daily Cases Top 11,000
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    subject: The quest for longer-lasting Covid-19 vaccines | CNN
    Event
    subject: SARS-CoV-2 RNA Can Persist in Stool Months After Respiratory Tract Clears Virus
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    subject: Putin's daughter flew to Munich 'more than 50 times' in two years, leaks reveal | Vladimir Putin | The Guardian
    Event
    subject: Monkeypox: Health Officials Investigate Possible Case in New York City
    Event
    subject: Wells Fargo advisors fined $7 million by U.S. SEC for anti-money laundering lapses

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